Insulin-induced iron loading in the rat brown adipose tissue: histochemical and electron-microscopic study.
نویسندگان
چکیده
In the present study we have reported an iron-loading in the rat brown adipose tissue (BAT) after 3-day treatment with insulin (4 IU/kg). Light microscopy showed numerous iron-positive cells (Perls' stain) mainly macrophages and brown adipocytes, while electron-microscopic examination revealed lipofuscin granules and phagosomes as iron-containing components. These results clearly indicate that iron participates in damaging of brown adipocytes.
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عنوان ژورنال:
- European journal of histochemistry : EJH
دوره 47 3 شماره
صفحات -
تاریخ انتشار 2003